Lutz Ackermann studied Chemistry at the University Kiel (Germany), and performed his PhD with Prof. Alois Fürstner at the Max-Planck Institut für Kohlenforschung (Mülheim/Ruhr, 2001).
After a postdoctoral stay at UC Berkeley with Prof. Robert G. Bergman, he initiated his independent research career in 2003 at the Ludwig Maximilians-University München. In 2007, he became Full Professor (W3) at the Georg-August-University Göttingen. His recent awards and distinctions include an AstraZeneca Excellence in Chemistry Award (2011), an ERC Consolidator Grant (2012), a Gottfried-Wilhelm-Leibniz-Preis (2017), an ERC Advanced Grant (2021) and the French-German SCF Prize (2022). The development and application of novel concepts for sustainable catalysis constitutes his major current research interests, with a topical focus on electrocatalysis and bond activation.
Thierry BERNOUD | C.E.O BIOSYNTHIS | Chemical engineer ESCOM 1987, passionated by Organic Chemistry
Started at Lab. MERCK-CLEVENOT 1989, Product Manager of innovative Liquid Crystals range for industrials ; such creating Thermochromic fabrics for a fashion dress at PACO RABANNE, shear forces & aerodynamism tests on Rafale jet at Dassault Aviation, creation of an original device for breast cancer detection..
Co-founder of MICROCAPSULES TECHNOLOGIES 1999 with Biopearl concept for long lasting perfumes in detergents, softeners UV-Filters for cosmetics. Melamin technology transfer to Perfumery houses,
Creation of BIOSYNTHIS in 2011 for a renewable and sustainable chemistry in Nouvelle Aquitaine.
Open 2nd production center near by Futuroscope (Poitiers) with Green Hydrogren unit in-house. About 20 Patents filed.
Guillaume is the Chief Scientific Officer of PILI, a french biotechnology and green chemistry company. He manages a pluridisciplinary team of 25 scientists working in the fields of metabolic engineering, bioprocesses, organic chemistry and process development as well as formulation.
Guillaume earned his phD in 2016 at ESPCI within the laboratory of Pr. Janine Cossy under the supervision of Christophe Meyer. His work focused on synthetic approaches towards an antitumoral natural product: Hemicalide, as well as the development of Gold-catalyzed cyclization of allenic carboxylic acids. Right after his phD, Guillaume became co-founder of recently-created biotech PILI and became CSO. The company rapidly built a scientific strategy aiming at the hemisynthesis of organics dyes and pigments from fermentation-derived intermediates. The hybrid technology and promising sector allowed the company to mobilize more than 15 M€ to develop and scale the technology at ton-scale. PILI is now launching the first biobased organic dyestuff for cotton, with a potential to cut by 75% the CO2 emissions associated to dyestuffs production. The company has filed 9 patent families and several publications in peer-reviewed journals.
Hélène Budzinski is a Research Director at CNRS and carried out her research activity at EPOC (Oceanic and Continental Environments and Paleoenvironments-University of Bordeaux).
She studied chemistry at « Ecole Nationale Supérieure de Chimie de Paris (ENSCP) ». She obtained her PhD from the Bordeaux University in 1993 in analytical chemistry. She has been working on ecodynamics and toxic impact of organic micropollutants. Her research activity is focused on one hand on the development of analytical tools for the determination of chemical pollutants (extraction, purification, quantification, identification methodologies). On the other hand she is involved in the study of biotic and abiotic phenomena affecting the presence of organic contaminants in the environment and their transfer towards organisms. She was awarded for her work the Silver medal of CNRS in 2017 and the SFC Sue award in 2022.
After a postdoctoral stay at Imperial College, London with Prof. Dominic Tildesley, he initiated his independent research career in 1996 on Molecular Dynamics at Instituto Superior Técnico, Lisbon, Portugal.
Since 2019, he is Full Professor of Physical Chemistry, Materials and Nano-Sciences at the same institution. His main research interests lie in the areas of molecular modeling of complex fluids and materials, including ionic liquids. Important contributions in this field comprise the development of a widely used systematic force field for MD simulations of ionic liquids and the analysis of nano-segregation phenomena in that novel class of fluids and their mixtures. These studies resulted from a very fruitful collaboration with research groups at the Université Blaise Pascal Clermont-Ferrand and École Normale Supérieure de Lyon, culminating in the French-Portuguese SCF Prize (2022).
Marc Fourmigué is Research Director at CNRS at the Institut des Sciences Chimiques de Rennes (ISCR).
After a PhD thesis between Copenhagen (K. Bechgaard) and Orsay (P. Batail), he got a CNRS position at the Solid State Physics Laboratory (LPS) in Orsay in 1990. Following a scientific stay at UC Santa Barbara (F. Wudl) in 1994, he moved to the Institut des Matériaux Jean Rouxel (IMN) in Nantes in 1995, and then at Moltech-Anjou in Angers in 2002. He is working in Rennes since 2006 where he contributed to the formation of the new Institut des Sciences Chimiques de Rennes (ISCR, 200 academics, 90 technicians, engineers and administrative staff) as head of the team “Condensed Matter and Electroactive Systems” (MaCSE, 2006-2015), acting as deputy director of ISCR in 2012 and as director of ISCR since 2017. His research interests address the chemistry and the physics of the organic solid state, particularly in organic conductors, in crystals and soft matter, with expertise in crystal growth techniques, radical systems, intermolecular non-covalent interactions, chemical crystallography and phase transitions.
Hélène Gérard is professor in chemistry at Sorbonne University and carried out her research activity at Laboratoire de Chimie Théorique (Paris).
She studied chemistry at Ecole Normale Supérieur de Lyon. She obtained her PhD from the Montpellier II University in 2001, under the supervision of Odile Eisenstein. She has been working on modelling, using quantum chemistry methods, of the structure, properties and reactivity of organometallic species in complex reactional microenvironment (in presence of coordinating solvent, additives, …). Her interest started with transition metal complexes and have evolved toward coinage metals and main group organometalllics. Her main field of applications are homogeneous catalysis, description of self-assembly processes and electron transfer reactions.
presented jointly with Clotilde Policar
Christelle Hureau is the head of the “Alzheimer, Amyloids and Bio-Inorganic Chemistry (ALAMBIC, https://hureaulab.wixsite.com/equipeflcc)” group at the Coordination Chemistry Lab in Toulouse.
She did her PhD in Orsay (France) on the coordination chemistry of Mn-based structural models of the water-oxidizing centre in the Photosystem II and graduated in 2003. Then she made three post-docs at the frontier between chemistry, biochemistry and advanced spectroscopy and electrochemistry · She is interested in the impact of metallic ions in Alzheimer’s disease (AD) and other amyloid-related diseases, in the design and study of new drug candidates targeting copper ions, and of inorganic compounds able to tune the self-assembly of the Aβ peptide, involved in AD.
Angela Marinetti studied chemistry at the University of Torino (IT). She obtained her PhD from the Paris VI University in 1984, under the supervision of Prof. François Mathey.
During her doctoral thesis and the following ten years or so, she worked on low-coordinated phosphorus species (phosphinidenes and phosphaalkenes) and strained 3- and 4-membered phosphorus heterocycles. Since 1994, her research has been focused notably on the design of chiral phosphorus ligands for enantioselective organometallic catalysis, in the fields of palladium, rhodium, ruthenium, platinum and gold catalysis. Moreover, she has been working on the use of trivalent phosphines as nucleophilic organocatalysts, and she has introduced platinum NHC complexes as bioactive organometallics with potential anticancer applications. All these topics have been developed successively at the Ecole Polytechnique (1994-1997), at the Ecole Nationale Supérieure de Chimie de Paris (1998-2004) and at the Institut de Chimie des Substances Naturelles (ICSN) in Gif sur Yvette (since 2005). From 2015 to 2019, she was the Director of the ICSN.
Rosa Palacín Peiró, Research Professor
Research professor at ICMAB-CSIC in Barcelona with a career fully focused in rechargeable battery materials, initially nickel or lithium based and more recently covering alternative chemistries such as sodium-ion, magnesium or calcium. She has led diverse research projects with either public or industrial funding and is actively involved in the ALISTORE-ERI and the International Battery Association. She serves in the board of Batteries Europe ETIP, is associate editor for Chemistry of Materials since 2016 and has recently been named ECS Fellow (2021), recognized with the IBA Research Award (2021) and awarded the Miguel Catalán-Paul Sabatier Prize by the SCF (2022).
presented jointly with Christelle Hureau
Clotilde Policar is a professor in bio-inorganic chemistry at the Ecole normale supérieure (ENS-PSL) in Paris (Research group Metals in biology and redox homeostasis: https://ens-bic.fr/)
Her work focuses on the study metal complexes directly in cellular or biological environments using cutting-edge imaging techniques and non-conventional modalities (IR imaging and micro-X-fluorescence). On the one hand, her group designs metal complexes mimicking anti-oxidant metalloenzymes such as SOD or catalase. For their evaluation in cells, they combine functional characterization (bio-activity evaluation, including cell feedback to treatment with the antioxidants), with quantification, imaging and speciation study. On the other hand, her group has initiated work on metal-based probes, including metal–carbonyl as multimodal bio-probes and organelles trackers that they have validated for in IR and X-fluorescence.
https://orcid.org/0000-0003-0255-1650
Frédéric BOLZE | Assistant professor at Laboratoire de conception et application de molécules bioactives, University of Strasbourg
Associate professor at the University of Strasbourg’s Faculty of Chemistry & UMR 7199 – GDR IMABIO – France
After a Doctorat from the University of Bourgogne (France) and a Ph.D. from the University of Sherbrooke (Canada) under the supervision of R. Guilard and P.D. Harvey he joined the group of J.L. Sessler at UT Austin (USA) to pursue research on porphyrins and related compounds.
He was then appointed assistant professor in 2002 at the University of Strasbourg in the group of J.F. Nicoud to develop two-photon sensitive chromophores for biological applications. Frederic is mainly teaching organic chemistry. He is interested in scientific popularization, in particular all aspects of light and light – matter interaction from kindergarten to university and general public.
Julien DELAHAYE | CNRS searcher at Intitut Néel
Après un doctorat en physique obtenu à l’Université Joseph Fourier de Grenoble en 2000, il entre au CNRS en 2003 pour travailler sur les dynamiques électroniques lentes dans les isolants désordonnés. Il est aujourd’hui membre de l’équipe Magnétisme et Supraconductivité de l’Institut Néel, à Grenoble. Il participe depuis plus de 15 ans à des actions de vulgarisation scientifique sur le thème de la lumière et des couleurs : expositions, formations pour enseignants, interventions en milieu scolaire et dans des festivals de science, conférences grand public. Il est l’un des créateurs et contributeurs du site grand public 123couleurs.fr.
IADECOLA Antonella is a CNRS Research Engineer within the framework of RS2E’s activities at SOLEIL (France).
After receiving her Ph.D. in Material Science in 2011, she has spent three years as a postdoctoral fellow at Elettra (Italy) and ESRF (France). Since she joined the RS2E in 2015, her research interest has shifted from physics to energy storage. Currently, her research activity focuses on the operando investigation of the electrochemical mechanisms occurring in energy storage systems, such as rechargeable batteries and supercapacitors, using a wide panel of synchrotron-based techniques.
Annie LE GAL LA SALLE is a researcher at Institut des Matériaux de Nantes (IMN) Jean Rouxel in France.
She chairs the Fuel‐cell sub‐group of the Electrochemical Storage and Conversion of Energy team of IMN, is a member of the executive board of FRH2 French Research network (FR2044) devoted to Hydrogen, and manages the relations between IMN and the West Atlantic Marine Energy Community. She coordinates several collaborative programs devoted to solid oxide cells, with a special interest in enlarging operating conditions of these devices (as fueling cells with gaseous mixtures issued from wastes and polluted air, or electrolyzing seawater). She also provides several courses in engineering schools and at university.
Gabriel Loget is a CNRS researcher working in the fields of electrochemistry and material science.
He received his PhD in Physical Chemistry from the University of Bordeaux under the supervision of Prof. Alexander Kuhn. After that, he performed a postdoctoral stay at the University of California, Irvine. In 2014, he was awarded an Alexander-von-Humboldt postdoctoral fellowship for doing his research at the Friedrich-Alexander Universität of Erlangen-Nürnberg. In 2015, he joined the CNRS where he works on photoelectrochemistry for energy and light conversion.
Stéphane Sarrade est ingénieur Polytech Montpellier et Docteur Habilité en Génie des Procédés. Impliqué depuis de nombreuses années dans le développement de procédés pour la Chimie Verte, son domaine de recherche couvre l’utilisation des fluides supercritiques et celui des procédés membranaires.
Il intègre le CEA en 2005 après son doctorat pour rapidement diriger des unités de recherche et développement à Pierrelatte (chef de laboratoire), Marcoule (chef de service) et Saclay (chef de département), dans les domaines du génie des procédés, de la chimie analytique et du traitement et du conditionnement des déchets nucléaires. Il a été Président du Club Français des Membranes (CFM) et il préside depuis 2006 Innovation Fluides Supercritiques, une structure de transfert technologique qui regroupe des laboratoires français et internationaux ainsi que des industriels impliqués dans les procédés durables. Il était co-fondateur en 2014 de la start-up Inovalor qui développait des solutions durables pour le traitement des déchets.
Actuellement Directeur de Recherche du CEA, Stéphane Sarrade est aussi Directeur des Programmes Energies au sein de la Direction des Énergies. Cette direction gère de manière programmatique et stratégique l’ensemble des programmes de R & D au CEA dans le domaine des énergies bas carbones : nucléaires et renouvelables (Solaire, H2, Batteries, Réseaux, …). Plus de 2200 ingénieurs/chercheurs et techniciens du CEA sont impliqués au CEA dans ce domaine avec un budget annuel de recherche d’environ 400 M€
Her career path is based on the carbon cycle. After studying the mechanisms of transformation of carbonaceous organic matter during geological ages (kerogen and oil) by Electronic Paramagnetic Resonance during her thesis, at IFP Energies Nouvelles, she developed hydrotreating (HDT) and hydrocracking (HCK) catalysts dedicated to the conversion of fossil resource into fuels.
Aware of environmental issues and in order to keep the carbon sequestered, she has worked on the recycling of plastics and tires. Today, as a project leader, she is redirecting her research towards the production of carbon-free energy and the conversion of CO2 emitted by factories using solar energy.
At IFPEN, she is co-inventor of more than 40 patents.
Mickael Capron has been an associate professor in the Department of Chemistry at the University of Lille since 2003.
He carries out his research work in the Vaalbio group of the Catalysis and Solid State Chemistry unit (UCCS). He focuses his research on the valorization of ex biomass alcohols such as glycerol, ethanol, etc… to obtain high added value molecules. His work has led to 85 publications and an H factor of 27. He has transferred part of his research activities into teaching by creating the Bioref Master’s degree which obtained the Erasmus Mundus label in 2019 and this until 2025.
Sara Cavaliere is Associate Professor in Chemistry at the University of Montpellier.
Her work aims at developing advanced nanostructured materials to enhance performance and durability of electrochemical energy conversion and storage devices, including fuel cells and electrolysers. Supported in 2012 by an ERC Starting Grant from the European Research Council, in 2017 she was awarded the CNRS bronze medal and appointed junior member of the Institut Universitaire de France. She co-authored over 60 scientific papers with a h-index of 24, 2 patents, 5 book chapters, and edited one book.
Thomas Cottineau is a CNRS researcher, working at the ICPEES institute, in Strasbourg, since 2014 when he joined the Photocatalysis & Photoconversion group.
Since his PhD (IMN, Nantes 2007), he showed a strong interest in nanostructured materials for light harvesting applications. After this first experience with hybrid materials for PV, he held post-doc positions in UQAM (Montreal, Canada) and LMSPC (Strasbourg) during which he developed & modified nanostructured materials and surfaces, mainly for photo-electrochemical applications.
His research at ICPEES aims to the development and improvement of metal oxide nanostructures for photo-oxidation reactions. A part of his work is devoted to the development of new photo-(electro)-catalytic analysis methods for a better understanding of the mechanisms involved during the photocatalytic reactions (light absorption, charge transfer and recombination) and in order to improve the materials in terms of performances and stability.
Sophie Hermans is an Inorganic Chemist who obtained her first degrees (‘Licence en Chimie’ and DEA) at UCLouvain in Belgium.
She carried out her PhD at the University of Cambridge (UK) under the supervision of Prof. Brian F. G. Johnson, working on mixed-metal clusters synthesis, then pursued postdoctoral studies in Cambridge (as JRF, Newnham College) with Prof. Sir John M. Thomas to immobilize the mixed-metal clusters in MCM-41 for heterogeneous catalytic applications. After moving back to UCLouvain with a FNRS ‘Chargée de recherches’ post, she started working on carbon-supported catalysts for sugar transformations and chemical functionalization of (nano)carbon surfaces. She obtained the FNRS ‘Chercheur Qualifié’ and Assistant Professor positions in 2005 and since then was promoted to ‘Professeur Extraordinaire’ and FNRS Research Director in 2020. Her research interests are still connected to inorganic molecular chemistry, carbon-based catalysts for biomass valorization, surface functionalization and nanostructured materials preparation.
Key Topics: Carbon ● Supported catalysts ● Functionalization ● Nanomaterials ● Biomass ●
ORCID : 0000-0003-4715-7964
Institutional website: https://uclouvain.be/en/research-institutes/imcn/most/research.html
Research Gate: https://www.researchgate.net/profile/Sophie_Hermans
URL Google Scholar: http://scholar.google.be/citations?user=_inQ2UQAAAAJ
Guillaume LEFEVRE is currently Chargé de Recherches in the i-CleHS institute (Institute of Chemistry for Life and Health Sciences, Chimie ParisTech, UMR8060).
He obtained his PhD in 2012 at the Ecole Normale Supérieure de Paris under the guidance of Dr. Anny Jutand, where he developed an expertise in molecular electrochemistry used as an investigation tool for mechanistic studies of transition-metal-calatyzed transformations. During this time, he worked in a close collaboration with the group of Pr. Carlo Adamo and Dr. Ilaria Ciofini (ENSCP ChimieParisTech, Paris), where he acquired skills in computational chemistry (DFT techniques applied to organometallic species). During a postdoctoral fellowship in the group of Prof. Peter Legzdins (University of British Columbia, Vancouver, Canada, 2012-2014; DOW Chemicals Fellowship), he worked in the field of C─H activation of saturated hydrocarbons involving tungsten nitrosyl complexes. He joined the Commissariat à l’Energie Atomique (CEA, group of Dr. Thibault Cantat) as a Chargé de Recherches (CNRS) in September 2014, focusing his research activity on two main axes : the development of new methodologies for the valorization of CO2 and its derivatives on one hand, and the development and mechanistic understanding of new low-valent iron-catalyzed coupling processes on the other hand. In 2019, he moved back to Paris, in Chimie ParisTech, in the Catalysis, Synthesis of Biomolecules and Sustainable Development team (CSB2D, directed by Dr. Virginie Vidal) of the i-CLeHS institute. He keeps developing new projects related to the reactivity of non-noble metals in catalysis, with a particular focus on low-valent iron chemistry and a strong interest in physical methods applied to the understanding of the mechanisms involved in those transformations. His research programs are so far supported by an ANR (2016-2020) and an ERC StG grant (2020-2025).
Célia Bonnet obtained her PhD thesis on the complexation of lanthanide cations by biological ligands in 2006 from the University of Grenoble and under the supervision of Dr Pascale Delangle et Pascal Fries.
She then moved to Trinity College in Dublin in the group of Pr. Thorri Gunnlaugsson where she worked on the synthesis and characterisation of luminescent probes. She obtained a CNRS position in 2010 in the Centre de Biophysique Moléculaire in Orléans, and was promoted as a CNRS research director in 2022. She is interested in the design and characterization of MRI contrast agents sensitive to different stimuli such as the presence of zinc or copper, as well as quantification and specificity problems associated to this detection. She is the author of 55 peer-reviewed articles, 5 book chapters and 1 patent, and the PI of several funding contracts such as ANRs, PCSI Inserm Aviesan, La Ligue Contre le Cancer, France Life Imaging, PHC, CNRS MITI, Maison de la Chimie…
Clément is currently a CNRS researcher in the Laboratoire de Catalysis, Polymerization, Processses and Materials (CP2M – UMR 5128), in Lyon (France).
He earned the Agrégation of Science Physiques in 2009 and graduated in 2010 from the École Normale Supérieure de Lyon (France). He received his Ph.D. degree in 2013 from the University of Grenoble (France) for his work on the coordination chemistry and reactivity of low-valent f-element compounds, performed under the supervision of Dr. Marinella Mazzanti. He then joined Prof. John Arnold’s group at the University of California, Berkeley (USA) for postdoctoral training where he studied the activation of small molecules by transition metal complexes. His current research interests deal with surface organometallic chemistry and cooperative effects in catalysis. Clément has authored 46 scientific papers, tackling problems in inorganic and organometallic chemistry with elements from across the periodic table. He has been laureate of several prestigious research grants, such as the CNRS MOMENTUM in 2017 and the ERC Starting Grant in 2021 and was the recipient of the CNRS bronze medal in 2022.
Carole Duboc is Research Director (DR1) at CNRS and distinguished for contributions to inorganic chemistry especially for the elucidation of the magnetic properties of metal complexes by combining spectroscopic techniques and theoretical chemistry, and for the design of bio-inspired complexes containing metal-sulfur bonds to develop structural and/or functional models of metalloenzymes.
Dr. Duboc received the CNRS Bronze Medal (2007), and awarded the SCF Physical Chemistry Division Prize as a young researcher (2007) and the SFC Coordination Chemistry Division Prize (2022) as a senior researcher. She has published over 145 scientific papers.
Yann Pellegrin obtained his PhD in coordination chemistry in 2004, in Orsay, on the subject of the artificial photosynthesis, under the supervision of Pr. Ally Aukauloo. He then went to Dublin City University in Ireland for a period of 3 years.
There, he worked on luminescent probes for biological media. He was hired as a CNRS fellow in 2007 in the CEISAM laboratory in Nantes University where he has been working on dye sensitized solar cells and the field of solar fuels. He is particularly interested in the synthesis and photochemical study of copper(I) complexes. More precisely, he works on their photochemical properties in the field of organic photocatalysis and he focuses on ways and means to stabilize their structure without altering their reactivity. He is co-author on more than 100 research articles, and has a keen interest in general public scientific outreach.
Simon Tricard
Laboratoire de Physique et Chimie des Nano-Objets
INSA, CNRS, Université de Toulouse
Valerie Andre has an engineer’s degree in biochemistry and a PhD in biomaterials from Lyon University (France).
She joined BASF Beauty Care Solutions research team to first set up and lead the Skin Engineering platform, developing the skin model portfolio to evaluate cosmetic ingredients efficacies. Since 2014, she’s one of the BASF Scouting and Communication Experts and contributes to BBCS innovation by setting up new R&D partnerships.
Alexandre Dazzi is a tenured Professor of physics at Université Paris-Saclay and works in the Institut de Chimie Physique. Alexandre does research focused on the infrared domain and teaches Nanoscience at the Université Paris-Saclay.
He has a physics background with a focus on optics and near-field techniques. He has an undergraduate degree in material science and obtained his Ph.D. in 1998 at the Université de Bourgogne. In 2000, Alexandre took an associate professor position at the CLIO FEL facility, where he worked on near-field techniques in the infrared. After inventing and developing the AFM-IR technique, Alexander has worked to improved AFM-IR instrumentation and has focused heavily on the study of biomolecule production by microorganisms. Alexandre has also developed a user facility, MUSIICS, based on AFM-IR systems and now collaborate with many groups in the Université Paris-Saclay in different domain like astrophysics, culture heritage, polymer science, microbiology.
He was the 2009 laureate for instrumentation prize from the Societé Francaise Division de Chimie Physique. He was also associated with R&D 100 awards in 2010 and the Microscopy Today 2011 Innovation Award for the nanoIRTM and received the Ernst Abbe Award in 2014 from the New York Microscopical Society.
Dominique Delbrayelle was born in 1972 in France. He graduated from ESPCI (Paris, France) in 1995.
He joined the SEAC company (now Minakem) in 1997. First in charge of the analytical development department, he evolved in the organization as the company grew from SEAC to Minakem and then in the Minafin group. He occupied various positions in R&D such as process optimization, plant support, process development team management, R&D laboratories management, and project management. Since 2014, he is the Scientific Director of Minakem. In this position, he uses his experience in all aspects of process development to support the business development teams and the R&D teams.
Claire Delacour is a Flow chemistry Engineer at Seqens where she developed continuous flow processes at the pilot scale.
She graduated with an engineer degree in chemistry and a Master degree in Bioprocesses and chemical processes from the National Polytechnic Institute of Chemical Engineering and Technology (ENSIACET). In 2017 she joined the group of Simon Kuhn at KU Leuven for her PhD. She developed new millifluidic devices assisted by ultrasound to perform chemical processes involving solid particles as reactant, catalyst, or product by keeping the flow of particles constant and controlling the particles sizes.
F.Delbecque is head of labs & application center in France, Spain & Germany in charge to develop paint for major OEM (Renault Nissan Stellantis JLR…)
Chemist & Engineer in materials science, more than 25 years in automotive industry in different positions as paint line manager or project leader but always linked to paint product & process. Now I’m in charge of a team around 60 persons (PhD, engineer technicians) in charge to develop new colors for major automotive company. The scope of responsibility starts from color design with OEM means how to translate in term of color the marketing & design inspiration, this development process includes to find the best solution in term of cost, process robustness and approval (paint durability). Last couple of years this process includes the new automotive challenges as sustainability in term of product & customer process (global C02 & COV footprint). Last 2 years Frederic was the BASF project leader for Oli the new concept car of Citroën.
Sylvie Dhulut carried out her PhD thesis in total synthesis under the supervision of J. Ardisson and A. Pancrazi with the collaboration of Pierre Fabre Laboratories.
She then performed her postdoctoral research in total synthesis in the Professor D. Enders laboratory in Germany. After one year of medicinal chemistry in collaboration with UCB Pharma under the supervision of Pr S. Routier at ICOA, she began her career at Oril Industrie (Servier) in 2007 as a Process chemist in the Chemical Development Department of the Industrial Research Center. Since 2007, she is in charge to develop and optimize API (Active Pharmaceutical Ingredient) synthesis in order to transfer them to pilote plant and production. She joined the Sustainable Chemistry Group of Oril Industrie in 2014.
Simon Gianordoli is Manager ChemTech, Digital Transformation & SME at France Chimie in Paris (https://www.francechimie.fr / https://www.francechimie.fr/la-chemtech).
Simon is managing the ChemTech network, representing the chemical start-ups in France. The ChemTech, founded by France Chimie and French Public Investment Bank (Bpifrance) supports new the actors of the French chemical industry, aiming for a greener and resilient industry in the 21st century.
Simon deals as well with the digital transformation of chemicals companies, by promoting Industry 4.0 topics and competitiveness of the chemical industry through digitalisation : Artificial Intelligence (IA) applications, Cybersecurity of industrial sites, transport digitalisation, predictive maintenance etc.. Finally, Simon is working on SMEs financing : export strategy, funding tools for decarbonation and digitalisation.
Romain Laher graduated from the École Nationale Supérieure de Chimie de Paris (ChimieParisTech, France) in 2015.
After 2 years in the perfume industry in the company Expressions Parfumées, he joined the group of Pr. Véronique Michelet in 2017 at the University de la Côte d’Azur at Nice. His work focused on the synthesis of odorant compounds for perfumery by gold catalysis methodologies. He obtained his PhD in December 2020. He now holds the position of R&D engineer in flavor extraction at Boisé France.
Fannie is science communicator in a scientific museum, in Paris. She collaborates with the media to communicate on topics related to chemistry, including green chemistry and issues related to plastics, to the general audience.
Fannie LE FLOCH, obtained her Ph.D. in polymer physico-chemistry from the University of Paris XII in 2022. Her specialty is the research of stimuli-responsive nanovectors based on biobased polymers. In addition to her research, she is strongly involved in science communication. Her research work was published as comics for general audience. She works as lecturer at a scientific museum, in Paris and collaborates with different media to elaborate scientific materials for social networks. Since September 2022, she is expert for climate comity in TF1, supporting the journalists of the TV channel on topics related to chemistry, especially green chemistry and contemporary issues related to plastics. Her involvement in green chemistry as Young Chemist was awarded by European Chemical Industry Council (CEFIC) in 2022.
Jean-Marc Petat graduated from ENSAIA Nancy. He then performed his research for CIRAD in French Guyana.
After one year, he began his career at BASF France division Agro in 1990 as Registration Manager. Since 2018, he is Head of Sustainable Agriculture, Communication and Public affairs and since 2019, he is also in charge of BASF Agricultural Solutions EMEA West.”
[ CV soon available]
Lydia Sosa Vargas is a CNRS researcher at the Institut Parisien de Chimie Moléculaire, Sorbonne Université since 2017. Originally from Mexico, she obtained her PhD from the University of East Anglia in the UK.
She carried out her first postdoctoral position in Japan at the National Institute of Advanced Industrial Science and Technology. In 2015, she joined the Polymer Chemistry team at Sorbonne University for her second postdoc before being recruited by the CNRS as a tenured researcher. Her research interests involve the molecular design and synthesis of pi-conjugated materials for applications in organic electronic and photonic devices, and supramolecular self-assembly at the nanoscale. Lydia is currently president of the Ile-de- France section at the Societé Chimique de France. She is also member of the of the French Polymer group, the Royal Society of Chemistry and the Polymer Division within the International Union of Pure and Applied Chemistry (IUPAC).
Emmanuel is supervising Product Stewardship, Product Service and EHS Masterdata for BASF Beauty Care Solutions France.
Biochemist by training, and Cosmetic Safety Assessor from Vrije University of Brussels, he works for 30 years in cosmetic ingredient industry. He managed different activities in raw material control & validation, international product registration, worldwide customer support and product quality to acquire a robust experience on cosmetic active ingredients. His daily challenges: following constantly moving international regulations to cover its portfolio of products and to answer to customers’ needs and wishes.
Dr. Bassani obtained a Bachelor’s degree in chemistry at the University of Louvain-la-Neuve, followed by PhD in Chemistry at Northwestern University under the guidance of F. D. Lewis.
He joined the CNRS at the University of Bordeaux in 1997 after postdoctoral fellowships with J. Wirz and J.-M. Lehn. He is the recipient of the Inter-American Photochemical Society young investigator award, the Grammaticakis-Neumann Prize of the Swiss Chemical Society, and the young investigator prize of the French Chemical Society (Physical Chemistry Division). His research interests span the use of supramolecular forces for controlling the interactions between molecules and light.
Dr. Etienne Brachet received in 2013 his PhD degree from the Paris XI University (Paris, France) under the direction of Drs. S. Messaoudi and M. Alami.
In 2014, he obtained a postdoctoral position in the research group of Prof. Dr. Burkhard König at the University of Regensburg (Germany). The same year he was recruted in the research team of Prof. Philippe Belmont at Paris City University as an Assistant Professor. He obtained his habilitation degree from this university in 2020 and recently received the “Enseignant-Chercheur 2021” award given by the Organic Division of the French Chemical Society (Prix Jean Normant). His research focuses on the development of new photoredox reactions toward the synthesis of heterocycles
Rafael Gramage-Doria received his Ph.D. from the University of Strasbourg (France) under the supervision of Dominique Matt and Dominique Armspach.
After postdoctoral research with Joost N. H. Reek at the University of Amsterdam (Netherlands) and later with Takashi Ooi at Nagoya University (Japan), he was appointed as a CNRS researcher at the Institute of Chemical Sciences of the University of Rennes 1 (France), where he obtained his Habilitation Diploma (2019). He is author of 45 publications and a book chapter, and he has delivered >30 (inter)national lectures. His research activities are supported by different funding agencies (ANR, CNRS, Universite de Rennes 1, Prestige Marie Curie, COST, Rennes Metropole, Region Bretagne, China Scholarship Council). Current research interests include transition-metal catalysis for fine chemicals and green chemistry applications, C–H bond functionalization, supramolecular and coordination chemistry, and supramolecular and bio-inspired catalysis. Besides several recognitions, he has been awarded a JSP Bürgenstock Fellowship and the Jean-Pierre Sauvage young researcher award from the SCF-DCO 2022.
Jennifer Morvan was born in 1995 in Pontivy (56, France). She studied chemistry at the Ecole Nationale Supérieure de Chimie of Rennes during five years where she specialized in organic synthesis.
She was graduated of engineering and master degree in 2018. She joined then the “Organometallics: Material and Catalysis” team (OMC) of the Rennes Institute of Chemical Sciences (ISCR) for her PhD supervised by Dr Marc Mauduit and Dr Christophe Crévisy. Her work consisted in the development of new ruthenium based complexes for stereoselective olefin metathesis. Synthesized as racemates, optically pure ruthenium complexes were obtained after chiral resolution by chiral preparative HPLC. Those novel catalysts enabled highly enantioselective Ring-Opening Cross-Metathesis and Cross-Metathesis transformations. She took also part in the development of the first Z-selective metathesis in continuous flow mode. After PhD graduation in December 2021, she is currently working as post-doctoral fellow with Dr Marc Mauduit and Dr Yann Trolez on polyynes synthesis by Mo-catalysed alkyne metathesis.
She has been awarded the 2022 Henri Kagan thesis prize of the Organic Chemistry Division (DCO) of the French Chemical Society (SCF).
Svetlana B. Tsogoeva is Professor of Organic Chemistry at the Friedrich-Alexander-University of Erlangen-Nuremberg, Germany, since February 2007.
She received her Diploma in Chemistry with Distinction in 1995 from St. Petersburg State University, where she completed her doctoral thesis in 1998 on the “Synthesis of Modified Analogues of Steroid Estrogens” supported by Procter & Gamble. In 1998, she moved to the Johann Wolfgang Goethe-University Frankfurt am Main, Germany, for a postdoctoral project under the sponsorship of the DFG, German Research Foundation. In July 2000 she joined the Degussa AG Fine Chemicals Division in Hanau-Wolfgang, Germany as a research scientist, where she has been working on the synthesis and the application of new oligopeptide catalysts for the enantioselective Julia-Colonna asymmetric epoxidation of olefins. In January 2002 she was appointed a First Junior Professor in Germany at the Georg-August-University of Göttingen, where she established her own research group supported by BMBF, DFG, FCI and Degussa AG. Her awards and distinctions include the Otto-Röhm Research Award and the Thieme Chemistry Journal Award in recognition of her contributions in the field of asymmetric organocatalysis. Her research is currently focused on organocatalyzed domino reactions and one-pot processes, photoracemization methods, deracemization of chiral bioactive compounds, and synthesis of natural product hybrids for medicinal chemistry.
Julien was born and raised in Armentières, France. For his Master studies, he attended CPE Lyon and the University of Lyon 1, where he worked in the laboratory of Prof. Olivier Baudoin, and graduated in 2014.
In the fall of that year, he enrolled the collaborative PhD program between GlaxoSmithKline and the University of Strathclyde working in the area of copper-catalyzed cross-coupling reactions under the supervision of Prof. Allan J. B. Watson and Dr. Albert Isidro-Llobet. He earned his PhD in Chemistry in March 2018. Afterward, he undertook a postdoctoral appointment at the Scripps Research Institute with Prof. Phil Baran, working on the design of a suite of new P(V)-based reagents and the development of electrochemically driven metal-catalyzed reactions. In December 2020, he started his independent career as a CNRS researcher in the SCORE lab at the ICBMS of Lyon focusing on the development of transition metal-catalyzed electrochemical transformations.
Alain Wagner is Director of Research at the CNRS and heads the BioFunctional Chemistry team of the UMR 7199 at the Faculty of Pharmacy in Strasbourg.
He is interested in manipulating living systems through the use, in situ, of chemical reactions capable of operating in complex biological media. His work particularly focusses on development of cleavable linkers and payloads with new or combined mode of action for safer Antibody Drug Conjugate (ADC) and on the use of chemistry to intercept reactive metabolites in living organisms. Alain also pioneer a microfluidic technology allowing for the analysis and sorting of large population of single cells on the basis of their secretory activity. Combining research and technology transfer Alain is author of more than 160 peer reviewed publications, inventor of 30 patents and co-founder of 5 start-ups.
Federica Agostini, Maître de Conférences since 2016 at the Institut de Chimie Physique (UMR8000) of the University Paris-Saclay (France);
She received her PhD in 2010 in the framework of a dual program between the University Pierre et Marie Curie in Paris (France) and the University Sapienza in Rome (Italy), where she also conducted her undergraduate studies in theoretical physics. The title of her PhD thesis, done under the supervision of Prof. Giovanni Ciccotti and Prof. Rodolphe Vuilleumier, is “Study of the transfer process of one excess proton in water via molecular dynamics simulations”. She did a one-year postdoc with Prof. Rodolphe Vuilleumier at the École Normale Supérieure in Paris and then she started a six-year postdoc with Prof. E. K. U. Gross at the Max-Planck Institute of Microstructure Physics in Halle (Germany) from 2010 until 2016. During this second postdoctoral experience she started working on the exact factorization of the electron-nuclear wavefunction to treat photochemical ultrafast processes with excited-state molecular-dynamics techniques, a theory and a computational method that she develops still nowadays.
Isabelle Compagnon is Maître de conférences at Université Claude Bernard Lyon 1 (Lyon, France). Her research activities take place at Institut Lumière Matière, an interdisciplinary CNRS institute dedicated to the production and use of light for the manipulation and interrogation of matter ranging from the bulk to the atom.
After a curriculum in Physics, she graduated in Molecular Sciences in Lyon in 2003. She specialised in Molecular Spectroscopy, and in particular in the coupling of Mass Spectrometry with laser spectroscopy, during her post-doctoral stay at the Free Electron Laser FELIX in the Netherlands. She was appointed Maître de conférences in Lyon in 2005, where she further developed laser-ions interactions instrumentations, ranging from the XUV to the IR domain in order to address fundamental Molecular Physics questions and Analytical Chemistry challenges. In the past 10 years, her research interest has focused on carbohydrates and she pioneered the use of the IR spectroscopic fingerprint as an additional analytical dimension in glycomics workflows. Her seminal work on the anomeric memory led to a patented carbohydrate sequencing technology; and to the creation of the Glycomics platform of the University of Lyon IROGLYPH, which hosts industrial research collaborations and external academic users. She was distinguished by the Institut Universitaire de France for her efforts to develop and translate Molecular Physics approaches for Analytical Chemistry and Glycomics.
Ali Abou-Hassan obtained his Ph.D. in physical-chemistry (supervised by V. Cabuil) in 2009. His Ph.D. was awarded by the French Chemical Society in 2010 with the thesis prize in physical-chemistry.
He pursued his training by a post-doc (with H. Möhwald and D. Wang, MPIKG, Germany) in 2010 which provided him expertise in plasmonic nanomaterials and self-assembly. He was recruited in 2010 as an assistant professor in PHENIX laboratory. Since 2010, he has developed his own multidisciplinary research ranging from setting up new synthesis and self-assembly strategies for the elaboration of multi-scale multifunctional materials combining his knowledge in physico-chemical microfluidics and colloidal chemistry. Fascinated by out of equilibrium phenomena he studies the impact of cells using material science and physical-chemistry approaches on the intrinsic properties of nanomaterials and the auto-organization of oscillating inorganic chemical reactions. In 2016 he defended his habilitation in chemistry (HDR) at Sorbonne University. In 2022, he was appointed junior member of the Institut Universitaire de France.
Cyrille Costentin received his undergraduate education at Ecole Normale Supérieure Paris-Saclay and pursued his graduate studies at the University Paris Diderot (Paris 7) where he received his Ph.D. in 2000 under the guidance of Prof. J-M. Savéant and Dr. P. Hapiot.
After a postdoc at the University of Rochester, he joined the faculty at the University of Paris Diderot as Associate Professor in 2001. He was promoted Professor in 2007. His area of expertise includes mechanisms and reactivity in electron transfer chemistry with particular recent emphasis on electrochemical and theoretical approaches to proton-coupled electron transfer processes and catalytic processes for small molecule activation. He is an expert in molecular electrochemistry and was a Visiting Scholar at Harvard University from 2016 to 2019 working with Prof. D. G. Nocera. In September 2019 he joined the Département de Chimie Moléculaire at the Université Grenoble-Alpes where he is now leading the group “Electrochimie Moléculaire et Photochimie Redox”.
Sandrine Lévêque-Fort is a CNRS Researcher Director at the Institute of molecular science (ISMO) in Paris Saclay University.
She obtained her PhD on the development of a new acousto-optic imaging approach for imaging through scattering media in ESPCI. She then became a postdoctoral fellow at Imperial College, where she started to develop time resolved fluorescence microscopy. She joined the CNRS in 2001 to develop different strategies to improve spatial and temporal resolution for fluorescence microscopy (FLIM-FRET imaging) or by introducing plasmonics substrates to engineer fluorescence emission. Since 2012, her research is focused in super-resolution microscopy. In particular, she develops new approaches in single molecule localization microscopy to enhance 3D resolution and thus revealing cellular nano-organization, but also accessing parameters such as spectra or lifetime at the nanoscale.
Title : Modulated excitation for enhanced single-molecule localization microscopy
Marc Robert was educated at the Ecole Normale Supérieure (Cachan, France) and gained his Ph.D. in 1995 from Paris Diderot University under the guidance of Claude Andrieux and Jean-Michel Savéant.
After one year as a postdoctoral fellow at Ohio State University (USA), working alongside Matt Platz, he joined the faculty at Paris Diderot University as Associate Professor (1997). He was promoted to full Professor in 2004, and distinguished Professor (Classe exceptionnelle) in 2019 at Université de Paris. He became a junior Fellow of the University Institute of France (IUF) in 2007 and a senior Fellow in 2017. He was a JSPS (Japan Society for the Promotion of Science) research Fellow (2015). Among various distinctions, Marc Robert received the first International Prize Essential Molecules Challenge from Air Liquide (2016) and the Chemistry and Energy Research Prize from the French Chemical Society (2019). In May 2022, he was renewed as Senior member and Innovation Chair at the Institut Universitaire de France for the next five year. His interests include electrochemical, photochemical, and theoretical approaches of electron transfer reactions and reactivity in chemistry, as well as catalytic activation of small molecules, mainly CO2 and N2.
Laura Scalfi studied at the École Normale Supérieure (Paris) from 2014 to 2018.
She then started a doctoral degree in physical and theoretical chemistry at the laboratory PHENIX under the supervision of Dr. Benjamin Rotenberg. She received her Ph.D. from Sorbonne Université (Paris) in 2021 and has been awarded for her work the Prize L’Oréal-UNESCO For Women in Science in 2021. Her research is turned to the physical chemistry of interfaces, developing theoretical and simulation tools, using in particular enhanced sampling. Her Ph.D. focused on the interface between electrode and electrolytes and the impact of the metallicity of electrodes on the structure, dynamics, surface tension and performances of capacitors for energy storage.
She has recently been awarded the 2022 Ph.D. prize of the Physical Chemistry Division (DCP) of the French Chemical Society (SCF).
She is currently working as a postdoctoral researcher at the Freie Universität Berlin (Germany) with Prof. Roland Netz on the modelling of non-markovian processes for applications to chemical reactions.
Delphine Chan-Seng is a CNRS researcher at the Institut Charles Sadron (Strasbourg, France), which is dedicated to the science of polymers and self-assembled systems involving researchers in chemistry, physico-chemistry, and physics.
She earned her Ph.D. degree in Polymer Chemistry (2007) from the University of Toronto (Canada) working on controlled radical polymerization focusing on atom transfer radical polymerization under seeded emulsion conditions and the investigation of acrylates polymerization under nitroxide-mediated polymerization conditions under the guidance of Michael K. Georges. She then conducted postdoctoral research at the University of Massachusetts at Amherst in the group of Todd Emrick, where she focused on the synthesis of polymers for targeted applications, such as the synthesis of aliphatic polyesters and their post-polymerization functionalization used as coatings for drug-elution cardiovascular stents, and the synthesis of peptide-based comb polymers used as non-viral vectors for gene therapy. In 2011, she was appointed CNRS researcher joining the Institut Charles Sadron (Strasbourg, France). Her research involves polymer chemistry, macromolecular engineering, and peptide synthesis to design polymers with specific properties for applications in biomedicine among others.
Élise DENIAU received her Ph.D. in 2010 in chemistry and physical-chemistry of polymers from the University of Le Mans (France) at the laboratory of Polymers, Colloids and Interface (now IMMM, UMR6283) by studying how to tune the aggregation of block copolymers into dynamic self-assemblies.
Subsequently, she joined the Macroarc Group of Prof. Barner-Kowollik at Karlsruhe Institute of Technology (KIT, Germany) as a post-doctoral fellow. In 2012, she became an associated professor at the University of Pau (UPPA, France) in the Institute of Analytical Sciences and Physico-chemistry for Environment of Materials (IPREM, UMR5254). She currently focuses on the controlled synthesis of functional polymers and colloids and their physico-chemical properties in aqueous media.
Her research activities focus on understanding the relationships between the chemical structure of amphiphilic block copolymers and their self-assembling properties in aqueous media. Her main objective is to develop macromolecular nanostructures such as dynamic micelles, microgels and polymeric nanoparticles that are responsive under different stimuli (pH, salt and/or temperature). She uses advanced macromolecular synthesis, based on controlled radical polymerization techniques (NMP, ATRP and RAFT) in order to finely control the chemical structure of polymers. Then, she implements a multi-scale experimental approach in order to characterize their physico-chemical properties using scattering techniques (light and neutrons). The obtained colloids find broad applications such as the detection of micropollutants in water, organic electronics, the release of active ingredients or the degradation of micro- and nanoplastics.
Dr. Arnaud Favier is a CNRS researcher at the Laboratoire d’Ingénierie des Matériaux Polymères in Lyon, France, which is dedicated to fundamental and applicative research on polymer science.
He is involved for many years at the interface between polymer chemistry and biomedical applications. With his expertise in RAFT controlled radical polymerization, he is currently developing well-defined fluorescent polymer probes for bio-imaging applications together with Marie-Thèrèse Charreyre. He obtained is PhD from a CNRS-bioMérieux joint laboratory at ENS Lyon before two post-docs at The University of New South Wales, Sydney, Australia and at Aix-Marseille University, France. Before joining CNRS, he served as scientist for two biotech companies Ilypsa Inc. and Relypsa, Inc. in Santa Clara, CA, USA.
Nicolas Leclerc is CNRS research director at the Institute of Chemistry and Processes for Energy, Environment and Health (ICPEES) of Strasbourg (France), where he leads a team dedicated to the design and synthesis of organic semiconducting materials.
Its research interests are mainly focused on the synthesis and characterization of new materials for energy applications, such as organic photovoltaics and organic thermoelectricity.
He is an active member of the OERA GDR.
He has published over 85 scientific papers with a h index of 28.
Sylvie Tencé-Girault is Research Engineer for Arkema chemical group since 1988. She received her PhD in 1987 from the Paris XI Orsay University, studying the Peierls transition in blue bronzes.
She spent thirteen years in an Arkema research center in charge of a «Structure-Morphology and Thermal properties» laboratory. Then from 2001 to 2017, she worked at the ESPCI Paris in the group of Prof. Ludwik Leibler, she now holds a position at PIMM-ENSAM Paris within the framework of the Arkema Industrial Chair (Arkema / CNRS-ENSAM-Cnam ). Her research focuses on the structure and morphology of nanostructured polymeric materials in relation to both their chemical compositions and their macroscopic properties, in order to develop and design new materials for Arkema, from high-performance semi-crystalline polymers.
Laure Biniek a obtenu son doctorat en chimie à l’Université de Strasbourg en 2010. Après un post-doctorat à l’Imperial College London au sein du groupe de Iain McCulloch en 2011 et un second post-doctorat dans l’équipe de Martin Brinkmann à l’Institut Charles Sadron, elle a été recrutée comme chercheur CNRS en 2014 à l’ICS. Ses activités de recherche s’articulent autour des corrélations structure-propriétés des polymères conducteurs pour des applications en électronique organique et conversion d’énergie. Elle développe actuellement des polymères poreux conducteurs pour la thermoélectricité.
Ingénierie d’enzymes pour la catalyse de réactions non-naturelles
Introduction
Dans un contexte de développement durable, l’industrie se tourne progressivement vers des procédés qui respectent l’environnement et la santé, via par exemple le remplacement des catalyseurs industriels (généralement chers, toxiques et non recyclables) par des biocatalyseurs (les enzymes) qui réalisent les transformations biologiques dans l’eau et généralement à température ambiante. Cependant, la majorité des réactions industrielles n’existent pas dans la Nature et les enzymes ne sont donc pas capables de les catalyser, ce qui limite leur utilisation. Néanmoins, l’apparition d’outils de biologie moléculaire puissants a récemment permis de créer des enzymes capables de réaliser ces réactions. Notamment, Frances Arnold (prix Nobel de chimie 2018) modifia par évolution dirigée des cytochromes P450 (enzymes hémiques) afin de catalyser des réactions non-naturelles de transferts de carbènes [1]. Depuis, plusieurs protéines hémiques ont été évoluées pour les réaliser [2]. Quelques enzymes non hémiques mais toujours ferriques [3] ont également été décrites pour ces transformations ainsi qu’une seule enzyme non ferrique (enzyme à cobalt) [4] alors que d’autres métaux les réalisent en synthèse organique comme le cuivre, un métal abondant et peu cher. Par conséquent, nous nous intéressons à des enzymes à cuivre impliquées dans la dégradation des biopolymères, les MonoOxygénases Polysaccharidiques Lytiques (LPMOs) [5], pour réaliser des réactions non-existantes dans la Nature.
Références [1] P. S. Coelho et al., Science, 339, 6117, 307 (2013) [2] O. Brandenberg et al., Curr. Opin. Biotechnol., 47, 102 (2017) [3] N. Goldberg et al., J. Am. Chem. Soc., 141, 19585 (2019) [4] X. Yang et al., ACS Catal., 12, 2, 935 (2021) [5] Chylenski et al., ACS Catal., 9, 6, 4970 (2019) [6] V. Tiagi et al., Angew. Chem. Int. Ed., 55, 13562 (2016)
My research activities are mainly devoted to the development of multifunctional nanoparticles for image-guided therapy.
First, I was involved in the development of radiosensitizing nanoparticles made of a polysiloxane network functionalized by macrocyclic gadolinium chelates. Preclinical studies have revealed the potential of these nanoparticles for radiotherapy guided by magnetic resonance imaging (MRI) and paved the way for clinical trials of these nanoparticles identified by the acronym AGuIX® (phase 2 under progress). In parallel, we have developed radiosensitizing gold nanoparticles whose functionalization by gadolinium chelates and/or radioisotopes allows the monitoring of the biodistribution of these nanoparticles by MRI (gadolinium) and/or by nuclear imaging after their administration. These gold nanoparticles have a strong potential for MRI-guided radiotherapy, but it seems underexploited due to an essential but too rapid renal clearance.
In order to postpone the renal clearance and better exploit the radiosensitizing effect of gold nanoparticles, we are exploring strategies based on the use of biodegradable carriers such as maghemite nanoflowers and polymeric PLGA particles. The grafting of gold nanoparticles onto the nanoflowers and the encapsulation of gold nanoparticles within PLGA particles afford a greater vascular residence time and tumor retention time in comparison to that of the free gold nanoparticles. In addition, these carriers provide the nanostructure with additional properties that allow combining different imaging modalities and therapeutic activity.
My research career has been inspired by two fascinating fields: supramolecular chemistry and organic electronics.
The combination of both has given rise to supramolecular electronics, which bridges the gap between molecular and plastic electronics, through the formation of supramolecular semiconductors. In this sense, supramolecular chemistry provides the tools to achieve highly organized supramolecular structures with superior properties than those of the monomers. The supramolecular polymers arise through reversible bonds, such as hydrogen-bonding and/or other noncovalent interactions, establishing supramolecular order at the required scale of operation in organic electronic devices. Apart from obtaining the required structures for electronic communication, the molecular design is equally important. Not only molecules with appropriate optoelectronic properties should be designed, but with the ability to self-assemble into challenging shapes and dimensions. More recently, my research efforts are focused towards addressing the global energy crisis by reducing recombination problems in organic photovoltaic devices by introducing the Chiral Induced Spin Selectivity Effect (CISS) into chiral supramolecular polymers. In this case, supramolecular chemistry meets the power of chirality to provide directionality to charges and increase photovoltaic devices efficiency.
Mots-clefs : Procédés en milieux confinés, émulsification, modification de surface, polymérisation, séparation de phase, nanoparticules stimulables, matériaux intelligents
J’ai travaillé trois ans sur l’élaboration de revêtements intelligents avec des propriétés thermoréversibles interfaciales. Plus précisément, l’objectif de cette étude était de concevoir des revêtements fonctionnels (par post-fonctionnalisation de polymères plasma) qui réagissent via la chimie de Diels-Alder, une réaction thermoréversible entre un diène et un diénophile, et de comprendre leur réactivité interfaciale. J’ai ensuite travaillé un an (2018-2019) à l’Institut Charles Sadron (UPR 22) en tant qu’Attachée Temporaire d’Enseignement et de Recherche (ATER, CNU 33/62) dans l’équipe de Chimie Macromoléculaire de Précision – dirigée par Dr. Jean-François Lutz. Le but de ce projet était de fonctionnaliser la surface de nanoparticules de poly(acide lactique-co-glycolique) (PLGA), obtenues par nanoprécipitation, afin d’en optimiser la dégradation enzymatique. En effet, le PLGA est naturellement lentement dégradé par l’organisme. En 2019, j’ai rejoint définitivement l’Institut Charles Sadron en tant que Maîtresse de Conférences et je m’intéresse à la fonctionnalisation de (bio)polymères ou de particules polymères afin de contrôler les caractéristiques physico-chimiques et les morphologies (sphères simples, coeur-écorce, Janus) du système uniquement en modifiant l’environnement des particules (= particules de polymères stimuli-répondantes) comme la température, le pH, le rayonnement UV, la présence d’un champ électromagnétique par exemple.
Elena Zaborova is Assistant professor at Interdisciplinary Center of Nanoscience of Marseille (CINaM), Aix Marseille University.
She obtained her Ph.D. in organic and supramolecular chemistry at the University Pierre et Marie Curie in Paris. After 3 years of postdoctoral fellows she was appointed as assistant professor at Aix Marseille University in 2014. Her current research interest is mainly focused on the synthesis and photophysical studies of the materials for organic photovoltaics and OLEDs.
Dr. Christine Guérard-Hélaine received her PhD degree in 1999 from the Clermont-Ferrand university (France) under the supervision of Prof. J. Bolte.
In 1999, she obtained a postdoctoral position at university Mc Gill (Montreal, Canada) in the research group of Pr. R. Kazlauskas. The next year, she was recruited as assistant professor in the research group of Pr. O. Ploux at Paris VI university. Then she moved in 2008 to the Clermont-Ferrand university (UCA) after 5 years of childcare obligations. She obtained her habilitation degree in 2018. Her research focuses on the development of enzymatic methods for the preparation of high added value chiral compounds, sometimes involving chemical catalysts (hybrid catalysis), often in one-pot one-step cascade reactions. She is also interested in the research of new enzymatic activities via enzyme discovery or engineering.
Pierre Toulhoat graduated in 1980 from the École Normale Supérieure in Paris, where he completed a PhD thesis in geochemistry and mineral resources. He then joined the CEA, French Atomic Energy Commission, to work on hydro-geochemistry of uranium and rare-earth elements and, later, on the scientific bases of underground confinement of radionuclides and nuclear waste disposal.
In parallel, he developed analytical chemistry for environmental studies in the frame of a joint research unit he established with the University of Evry. In 2002, he joined CNRS and the University of Lyon, to set up the Institute of Analytical Sciences which he directed until 2012. In 2005, he became the scientific director of Ineris, the French national institute for industrial environments and risks. Associate Professor at the University of Lyon 1 until 2016, he is also a fellow of the French Academy of Technologies since 2010. He is presently chairing the division dedicated to environment and climate change. Pierre Toulhoat joined the BRGM/French Geological Survey (2016-2021) as deputy CEO and scientific director, and interim CEO (2016-2017). He has specially fostered the research, and international cooperation on mineral resources development. He currently chairs the scientific committee of ANDRA, National Agency in charge of radioactive waste management, and participates to several national and international scientific committees (IRSN, Mines de Paris PSL, European Program EURAD on radwaste management) and review boards in France and abroad.
https://www.researchgate.net/profile/Pierre-Toulhoat
https://scholar.google.fr/citations?hl=fr&user=7l3h1_QAAAAJ
Mónica Burriel is a CNRS Research Scientist and leads the Oxides for Nanoionic Devices group at the Materials and Physical Engineering Laboratory (LMGP, CNRS, Grenoble-INP) in Grenoble (France).
After her PhD in the ICMAB Institute (Barcelona, Spain), she worked in the Karlsruhe Institute of Technology (Germany), Imperial College London (UK) and IREC (Barcelona, Spain). She recently obtained her Habilitation degree by the Grenoble Alpes University (2021). She has an extensive expertise in the effect of the structure, microstructure and composition on the functional properties of oxide thin films. Her current research on thin films for electrochemical and memristive micro-devices focuses on the deposition (by ALD and MOCVD), structure/microstructure control and optimization of the electronic and ionic transport of functional oxides.
Philippe Goldner is a CNRS researcher working at the IRCP institute in Paris where he leads since 2009 the Crystals and Quantum State Dynamics group.
In 1993, he obtained his PhD at CNRS Bellevue laboratories and joined the CNRS to work on luminescent rare earth doped materials. He later moved to the French National Center for Telecommunication Studies and in 2002 to Chimie ParisTech graduate school, investigating materials for laser and optical amplifiers. In 2003, he started to shift his interest to applications of rare earth doped crystals in quantum technologies. His team currently develops these systems in the bulk form or as nanostructures to enable e.g. light storage at the quantum level or scalable quantum processors. He received a Stars of Europe award in 2020 and the CNRS Silver Medal in 2022. He also obtained in 2021 an ERC Advanced Grant to develop new hybrid materials for quantum photonics.
Sophie Tencé is a CNRS researcher since 2012, working at the “Institut de Chimie de la Matière Condensée de Bordeaux” (ICMCB) in the “Intermetallics, metals and composites” group.
After her PhD on intermetallic hydrides at LLB-CEA-Saclay/ICMCB-Bordeaux in 2009, she got a post-doctoral position at the Max Planck Institute for Chemical Physics of Solids in Dresden (Germany) in the group a Yuri Grin and Franck Steglich and then a post-doctoral fellow at the Néel institute (Grenoble) in the group of Olivier Isnard. She is interested in the modulation of catalytic, magnetic, electronic and transport properties via the insertion of light elements (H, B, C, N, O and F) in intermetallics made up of rare earths, transition elements and p-elements. Her work has notably led to the discovery of new unconventional iron-based superconductors, the first ones with a FeSi superconducting layer. In addition, she develops a new thematic on the topotactic fluorination of intermetallics which also opens up prospects in the field of fluorine batteries, and works on electride materials for the catalytic synthesis of ammonia under ‘mild’ pressure-temperature conditions.
Damien VOIRY is a graduate of the National School of Chemistry and Physics of Bordeaux (ENSCPB) and obtained his thesis at the Paul Pascal Research Center (CRPP) of the University of Bordeaux in 2010.
Damien then carried out a postdoctoral 2011 to 2016 in the group of Professor Manish Chhowalla from Rutgers University in the United States. His postdoc work focused on the modification of the crystal structures of metal chalcogenide nanosheets for electrocatalysis and electronics. Since February 2016, he has been a CNRS researcher (CR2) at the IEM in the DM3 department. His current research aims to study structure-property relationships for two-dimensional materials and heterostructures made from low-dimensional materials for energy applications and the fabrication of new membranes. In April 2017, Damien published 35 articles for an h factor of 18 and a citation count of over 3700.